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Showing posts with label Executive Branch. Show all posts
Showing posts with label Executive Branch. Show all posts

Wednesday, November 27, 2013

Exposure to Shift Work as a Risk Factor for Diabetes

Today's post was shared by Safe Healthy Workers and comes from jbr.sagepub.com

Using telephone survey data from 1111 retired older adults (≥65 years; 634 male, 477 female), we tested the hypothesis that exposure to shift work might result in increased self-reported diabetes. Five shift work exposure bins were considered: 0 years, 1-7 years, 8-14 years, 15-20 years, and 20 years. Shift work exposed groups showed an increased proportion of self-reported diabetes (χ2 = 22.32, p < 0.001), with odds ratios (ORs) of about 2 when compared to the 0-year group. The effect remained significant after adjusting for gender and body mass index (BMI) (OR ≥ 1.4; χ2 = 10.78, p < 0.05). There was a significant shift work exposure effect on BMI (χ2 = 80.70, p < 0.001) but no significant gender effect (χ2 = 0.37, p 0.50).
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Sunday, October 27, 2013

Increased in risk of specific NHL subtypes associated with occupational exposure to TCE

Trichloroethylene
Study published linking trichloroethylene exposure to cancer.

The chemical compound trichloroethylene (C2HCl3) is a chlorinated hydrocarbon commonly used as an industrial solvent. It is a clear non-flammable liquid with a sweet smell.

"Objectives We evaluated the association between occupational exposure to trichloroethylene (TCE) and risk of non-Hodgkin lymphoma (NHL) in a pooled 
analysis of four international case-control studies.

Methods Overall, the pooled study population included 3788 NHL cases and 4279 controls. Risk of NHL and its major subtypes associated with TCE exposure was calculated with unconditional logistic regression and polytomous regression analysis, adjusting by age, gender and study.

Results Risk of follicular lymphoma (FL), but not NHL overall or other subtypes, increased by probability (p=0.02) and intensity level (p=0.04), and with the combined analysis of four exposure metrics assumed as independent (p=0.004). After restricting the analysis to the most likely exposed study subjects, risk of NHL overall, FL and chronic lymphocytic leukaemia (CLL) were elevated and increased by duration of exposure (p=0.009, p=0.04 and p=0.01, respectively) and with the combined analysis of duration, frequency and intensity of exposure (p=0.004, p=0.015 and p=0.005, respectively). Although based on small numbers of exposed, risk of all the major NHL subtypes, namely diffuse large B-cell lymphoma, FL and CLL, showed increases in risk ranging 2–3.2-fold in the highest category of exposure intensity. No significant heterogeneity in risk was detected by major NHL subtypes or by study.

Conclusions Our pooled analysis apparently supports the hypothesis of an increase in risk of specific NHL subtypes associated with occupational exposure to TCE.

Thursday, October 3, 2013

Asthma related to cleaning agents: a clinical insight

 Cleaning workers are exposed to many substances ans irritants.Today post is from bmj.org.

In recent years, there has been a growing concern about the potential role of exposure to cleaning products in the initiation and aggravation of asthma. 

Epidemiological surveys have consistently documented increased prevalence3–5 and incidence6–8 rates of asthma in workers exposed to cleaning materials and/or disinfectants, especially in domestic cleaners3,4 and healthcare workers.

 In addition, some studies have reported an increased risk of work-related asthma symptoms in exposed workers.

However, there is still limited knowledge on the specific exposures and pathophysiological mechanisms involved in cleaning-related asthma.

Cleaning materials typically contain a wide variety of ingredients, some of which are respiratory irritants, such as chlorine-releasing agents and ammonia, while others are potential airway sensitizers.
 Asthma in cleaners has been mostly associated with the irritant effects of cleaning products, which may exacerbate asthma and, at high exposure levels, cause acute irritant-induced asthma (or ‘reactive airways dysfunction syndrome’)

Nevertheless, occasional case reports have ascribed occupational asthma (OA) due to specific airway hypersensitivty to components of detergents or disinfectants.2 Overall the determinants of cleaning-related asthma symptoms remain largely uncertain since most...
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Tuesday, October 1, 2013

An Official Statement on Environmental Toxins and Pregnancy

Today's post was shared by RWJF PublicHealth and comes from www.theatlantic.com

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For years, the debate over restricting the stew of industrial chemicals that we live in has suffered from a case of he said, she said.

Environmental groups sounded the alarm about the thousands of chemicals in our air, water, food, housewares, and shampoo that science suggests — but doesn’t outright prove — could make us sick. They warned about such commonly used substances as BPA (in cans and plastics), fire retardants (in furniture), and phthalates (in cosmetics). Chemical industry representatives countered that there is no clear evidence that their products are unsafe, and tighter regulation would squash innovation.

But now it’s about pregnant moms and unborn babies.

For the first time ever, the American Congress of Obstetricians and Gynecologists (ACOG) this week came out with a strong statement about the risks of environmental toxins to pregnant women and fetuses. Also for the first time, the group is going so far as to urge individual doctors to advocate for policy changes to protect women and babies from exposure.



“The scientific evidence over the last 15 years shows that exposure to toxic environmental agents before conception and during pregnancy can have significant and long-lasting effects on reproductive health,” wrote ACOG. Another group of reproduction specialists, the American Society...
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