Who is at risk?
Workers who make, use, or work near flavoring chemicals containing diacetyl or 2,3-pentanedione may be at risk. Settings where these exposures may occur include:
- Flavoring plants
- Microwave popcorn plant
- Commercial and retail bakeries
- Snack food and candy plants
- Dairy products and packaged vegetable oil plants (e.g., margarine, cooking oil)
- Other flavored food production plants.Exposures in the flavoring industry and in microwave popcorn production have caused workers to have severe lung disease. The burden of hazardous exposures and risk to workers in other settings remains unclear. However, it is important to consider the possibility of flavoring-related lung disease in workers who have been exposed to diacetyl or similar flavoring chemicals and have respiratory symptoms
About Symptoms
Symptoms are not present in all cases. When present, symptoms can range in severity. The main respiratory symptoms experienced by workers include:
- Cough (usually without phlegm)
- Shortness of breath on exertion
- Wheezing
- Fever, night sweats, or weight loss
- Frequent or persistent eye, nose, throat, or skin irritation
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