Wednesday, November 5, 2025

Workplace Toxins: A Hidden Epidemic

In his groundbreaking new book, The Formula for Better Health: How to Save Millions of Lives—Including Your Own, former CDC Director Dr. Tom Frieden draws on decades of experience leading public health efforts to reveal how to defeat the world's deadliest diseases. While the book covers many health threats, its principles are particularly relevant to one of America's most overlooked crises: occupational exposure to toxic substances.


The Invisible Threat in American Workplaces

Dr. Frieden emphasizes that promoting individual behavior change is not the core of public health—it's a symptom of public health failure. When public health succeeds, societal changes encourage individuals to make healthy choices as their default. This philosophy applies powerfully to workplace safety, where an estimated three million U.S. workers are potentially exposed to toxic substances like lead, forever chemicals, and nanoparticles.

Lead: America's Persistent Poison

Despite decades of awareness, lead exposure remains a critical workplace hazard. Research estimates that the direct medical costs of approximately 10,000 U.S. workers with high occupational lead exposures amount to $141 million per year, with combined direct and indirect costs exceeding $392 million annually. Even more alarming, reducing allowable occupational lead limits could produce annual societal benefits of almost $40,000 per highly exposed worker.

Studies show the risk of dying from heart diseases, such as heart attack or stroke, is 2 to 5 times higher among people with elevated blood lead levels—a relative risk equal to or higher than smoking, elevated cholesterol, and hypertension. Workers in battery manufacturing, construction, and firing ranges face particularly high exposure risks.

Forever Chemicals: The PFAS Problem

Per- and polyfluoroalkyl substances (PFAS), commonly referred to as "forever chemicals," represent an emerging occupational health crisis. Industrial workers involved in making or processing PFAS or PFAS-containing materials may have greater exposure than the general population. Firefighters and chemical manufacturing workers are particularly at risk, as PFAS are often used in foam to extinguish liquid fuel fires.

Research suggests associations between PFAS exposure and increases in cholesterol levels, lower antibody response to vaccines, changes in liver enzymes, and pregnancy-induced hypertension. Almost 100 percent of the U.S. population is exposed to at least one PFAS, but occupational exposures can be significantly higher.

Nanoparticles: The Frontier of Workplace Hazards

As nanotechnology expands, workers face new risks. Employees using nanomaterials in research or production may be exposed through inhalation, dermal contact, or ingestion. Scientific studies indicate that some of these materials are biologically active, can penetrate intact human skin, and have produced toxicologic reactions in the lungs of exposed animals.

The challenge? The potential health effects of occupational exposure to nanoparticles are not yet fully understood, but workers are already exposed in semiconductor fabrication, manufacturing, and research facilities.

The Workers' Compensation Connection

Improving occupational environments directly reduces workers' compensation claims in several ways:

Reduced Frequency: Eliminating or controlling toxic exposures prevents occupational diseases before they occur, thereby dramatically reducing the number of claims filed for conditions such as lead poisoning, respiratory illnesses, and chemical-related cancers.

Decreased Severity: When exposures are minimized early, workers avoid the chronic, debilitating conditions that generate the most expensive claims. Research shows that employers' costs include hiring and training replacements for injured workers, productivity impacts on coworkers, and hidden administrative time—all of which are reduced when prevention succeeds.

Long-term Savings: The benefits of reducing occupational lead limits alone could save almost $40,000 annually per highly exposed worker,  with similar cost-benefit ratios likely for PFAS and nanoparticle exposure controls.

Key Concept from Frieden's Formula

The most important concept from Dr. Frieden's work is this: "When public health succeeds, societal changes make the individual's default choices healthy." Applied to occupational health, this means creating workplaces where the safest option is the easiest option—through the use of engineering controls, proper ventilation, safer substitutes, and systemic protections, rather than relying on individual worker vigilance.

Key Takeaways

  1. Prevention Over Treatment: Occupational health improvements prevent diseases before they occur, reducing both human suffering and financial costs
  2. Three Million at Risk: Millions of American workers face daily exposure to lead, PFAS, and nanoparticles with potentially devastating long-term health consequences
  3. Massive Economic Impact: Occupational lead exposure alone costs nearly $400 million annually in health and productivity losses—a figure multiplied across all toxic exposures
  4. Workers' Comp Savings: Improved workplace environments directly decrease both the frequency and severity of workers' compensation claims
  5. Systemic Solutions Required: Individual protective equipment is not enough—workplace redesign, safer materials, and engineering controls create lasting protection
  6. Knowledge Gaps Remain: Despite known risks, the health effects of PFAS and nanoparticles are still being studied, making precautionary protection essential
  7. Hidden Costs Are Real: Beyond direct medical expenses, toxic exposures create productivity losses, training costs, and workforce disruption that severely impact employers

The Path Forward: As Dr. Frieden demonstrates in The Formula for Better Health, protecting population health requires moving beyond individual behavior to systemic change. For American workers, this means transforming occupational environments to eliminate toxic exposures at their source—creating workplaces where health is the default outcome, not an individual battle against invisible hazards.


Dr. Tom Frieden's "The Formula for Better Health: How to Save Millions of Lives—Including Your Own" is available now from MIT Press.

Blog: Workers' Compensation

LinkedIn: JonGelman

LinkedIn Group: Injured Workers Law & Advocacy Group

Author: "Workers' Compensation Law" West-Thomson-Reuters

Mastodon:@gelman@mstdn.social

Blue Sky: jongelman@bsky.social


© 2025 Jon L Gelman. All rights reserved.


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