IMIG 2014: Dr. Robert Weinberg speaks on Cancer Stem Cell Targeting Therapies

Dr. Weinberg focused on the importance of cancer stem cells in mesothelioma. The concept of a stem cell origin of cancer was first described over fifty years ago as a small subset of cells capable of re-initiating a clonal tumor, and there is evidence for both a stem cell origin of mesothelioma, and a stem cell population in the mesothelioma tumor microenvironment. These cells play an essential role in the invasion-metastasis cascade, they are risk to conventional chemotherapy, and are believed to underlie resistance and relapse in mesothelioma. Click here for a summary of the latest information on cancer stem cells in mesothelioma.

Click here to watch Dr. Weinberg’s Presentation

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IMIG 2014: Dr. Ravi Salgia presents “From Chaos to Mitochondrial Functionality”

Dr. Salgia summarized efforts from his group to bring mathematical modeling to the study of malignant mesothelioma and how the rules of this theory can be applied to consideration of mutations associated with mesothelioma, suggesting that DNA acts much likes fractals. He emphasized that the fractal dimensionality of mesothelioma cells is dramatically different from that of normal cells and that mitochondrial networks in mesothelioma can also be modeled with fractal analysis. Click here to learn more about this new approach to understanding mesothelioma and the biology of other cancer cells.

Click here to watch Dr. Salgia’s Presentation

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• Curcumin, special peptides boost cancer-blocking PIAS3 to neutralize cancer-activating STAT3 in mesothelioma (workers-compensation.blogspot.com)
• How asbestos exposure leads to mesothelioma (workers-compensation.blogspot.com)
• Systematic review of response rates of sarcomatoid malignant pleural mesotheliomas in clinical trials (workers-compensation.blogspot.com)
• Consequences of asbestos: New laboratory installed for research into pleural cancer (workers-compensation.blogspot.com)
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