Health Care Workers Suffer Exposures to Antineoplastic Drugs

A recent study reveals that health care workers may be suffering from occupational exposure to chemotherapy drugs while treating cancer patients.

"Antineoplastic drugs are pharmaceuticals commonly used to treat cancer, which are generally referred to as 'chemotherapy'. Several studies have shown that exposure to antineoplastic drugs can cause toxic effects on reproduction as well as carcinogenic effects. Presence of these drugs in the urine of hospital personnel has been widely studied and dermal exposure has been suggested to be the main route of exposure. 

The main focus has been on handling the concentrated drug during preparation and administration of antineoplastic drugs and several approaches have been proposed on how to control those. Handling patient excreta has been considered to be potentially harmful to nurses working with cancer patients, since antineoplastic drugs are known to be present in patient excreta (e.g. urine, saliva, sweat, faeces, vomit), but this has not been studied in great detail in occupational exposure studies. 

The identification of occupational exposure to antineoplastic drugs in sectors outside the hospital environment (i.e. veterinary medicine, home care, nursing homes and industrial laundries) showed that the number of workers potentially exposed to antineoplastic drugs is larger than previously estimated. "

Click here to read the series of articles in The Annals of Occupational Hygiene

Exposure to Antineoplastic Drugs in Two UK Hospital Pharmacy Units 
H. J. Mason, S. Blair, C. Sams, K. Jones, S. J. Garfitt, M. J. Cuschieri, and P. J. Baxter 

A Pooled Analysis to Study Trends in Exposure to Antineoplastic Drugs among Nurses 
Wouter Fransman, Susan Peelen, Simone Hilhorst, Nel Roeleveld, Dick Heederik, and Hans Kromhout 

Occupational Dermal Exposure to Cyclophosphamide in Dutch Hospitals: A Pilot Study 
Wouter Fransman, Roel Vermeulen, And Hans Kromhout 

Postulating a dermal pathway for exposure to anti-neoplastic drugs among hospital workers 
Hans Kromhout, Fred Hoek, Ruud Uitterhoeve, Roel Huijbers, Roderik F. Overmars, Rob Anzion, and Roel Vermeulen 

Occupational Exposure Limits for Therapeutic Substances 
Raymond Agius 

Read more about "occupational exposures" and workers' compensation:

Workers' Compensation: OSHA Targets Occupational Exposure to ...

Jul 12, 2013

The Occupational Safety and Health Administration today announced a new National Emphasis Program to protect workers from the serious health effects from occupational exposure to isocyanates. OSHA develops national ...

http://workers-compensation.blogspot.com/

Workers' Compensation: Chemical Exposure: Devastating ...

Jun 03, 2013

Chemical exposure in the workplace can have an insidious--yet devasating--effect on a worker. In a wide-ranging article, the New York Times presented an in-depth view of chemical exposure at furniture factories in North ...

http://workers-compensation.blogspot.com/

Workers' Compensation: Occupational Safety and Health ...

Jul 19, 2013

Workers' compensation claims result from heat stress and exposure. As the Mid-West and Northeast heatwave is now soaring to records temperatures, workers should protect themselves from heat exposure. Today's post was ...

http://workers-compensation.blogspot.com/

Related articles

• OSHA and NIOSH issue hazard alert on 1-bromopropane (workers-compensation.blogspot.com)
• OSHA announces outreach campaign to protect health care workers from hazards causing musculoskeletal disorders (workers-compensation.blogspot.com)
• Largest Study to Date Finds State Smoke-Free Laws Would Not Hurt Restaurant and Bar Business (workers-compensation.blogspot.com)
• Lead Paint - Industry Has Yet to Meet Its Responsibility (workers-compensation.blogspot.com)
• When Things Are Wrong In The Hospital - CDC Sets Guidelines To Notify Patients/Families (workers-compensation.blogspot.com)
• Breast Cancer Risk Doubles With Overnight Shift Work (workers-compensation.blogspot.com)

The 6 Things You Need To Do If You Are Exposed To Mercury

Elemental mercury is a silver, odorless liquid.

Today's post comes from guest author Catherine Stanton from Pasternack Tilker Ziegler Walsh Stanton & Romano.

Irving J. Selikoff Center for Occupational & Environmental Medicine at Mount Sinai School of Medicine has released a guide to treatment for elemental mercury ((the pure form of the metal, when it is not combined with other chemicals) exposure. There are other forms of mercury, such as compounds found in contaminated fish, known as organic mercury and those are not covered by the guide.
Workers who experience a one-time sudden exposure to any chemical substance at work, should:

1. Gather as much information as you can about the type and amount of exposure, including labels, Material Safety Data Sheets (MSDS), and the medical emergency phone number on the MSDS. 
2. If you are feeling ill, seek medical attention at an emergency department (ED) immediately. It is best if a medical toxicologist is consulted as part of your visit to the ED. They can be reached for advice about treatment by having the healthcare professional contact the Poison Control Center at 1-800-222-1222. 
3. You can call the PCC independently for recommendations as well.
4. Once the urgent situation has been taken care of, you may contact the nearest occupational health clinic in the country for recommendations and follow-up.
5. This fact sheet is not a substitute for medical care. The purpose is to direct the exposed worker to the proper medical provider. 
6. Report any exposure to your employer immediately. Complete an incident or exposure form. If none is available, write a memo informing them of the exposure incident (date, time, location, what you were doing in the area, and for how long). Keep copies and insist that documents are placed in your personnel files.

You can download a copy of the fact sheet by clicking here. It contains more information about the following topics:

Popcorn Lung Rules Return

How NIOSH's diacetyl exposure limits still shape flavoring-industry lung-disease claims

Exposed to "Forever Chemicals": NJ Workers' Compensation for PFAS Illness

Per and polyfluoroalkyl substances (PFAS), also known as "forever chemicals," are a growing concern in the workplace. These man-made chemicals are nearly impossible to break down and can build up in the body over time. Unfortunately, some New Jersey workers are facing serious health consequences due to PFAS exposure.

Smoke Signals for Compensation

Canadian Wildfire Smoke, Northeast Air Pollution, and the Coming Wave of Occupational Exposure Claims

Microplastics: Workplace Threat

Recent scientific studies and published articles have reported the dangers of microplastics and nanoplastics (MNPs) in the workplace and the consequences of occupational exposure to MNPs.

Asbestos Burden Persists Quietly

What a new national study reveals about mesothelioma, occupational exposure, and the future of workers' compensation claims.

Hazards exist in the surface refinishing business

University of Iowa, College of Public health, recently reported the death of a bathtub refinishingt technician who died from the inhalation of paint stripper vapors.

In 2012, a 37-year-old female technician employed by a surface-refinishing business died from inhalation exposure to methylene chloride and methanol vapors while she used a chemical stripper to prep the surface of a bathtub for refinishing. The technician was working alone without respiratory protection or ventilation controls in a small bathroom of a rental apartment. When the technician did not pick up her children at the end of the day, her parents contacted her employer, who then called the apartment complex manager after determining the victim’s personal vehicle was still at the refinishing company’s parking lot.

The apartment complex manager went to the apartment unit where the employee had been working and called 911 upon finding the employee unresponsive, slumped over the bathtub. City Fire Department responders arrived within 4 minutes  of the 911 call. The apartment manager and first responders reported a strong chemical odor in the  second story apartment. There was an uncapped gallon can of Klean Strip Aircraft® Low Odor Paint  Remover (80-90% methylene chloride, 5-10% methanol) in the bathroom. The employee’s tools and knee pad were found in the tub, suggesting the employee had been kneeling and leaning over the tub wall to manually remove the loosened original bathtub finish coat.

The factors contributing to this lethal exposure include use of a highly concentrated methylene chloride chemical stripper having poor warning properties (“Low Odor”); working in a small room without local exhaust ventilation to remove chemical vapors or provide fresh air; and working without a respirator that could have protected the employee from exposure.

Read More about "occupational exposure"

Breast cancer risk in relation to occupations with exposure to ...

Nov 23, 2012

"Odds ratios (ORs) were increased for the usual risk factors for breast cancer and, adjusting for these, risks increased with occupational exposure to several agents, and were highest for exposures occurring before age 36 .

http://workers-compensation.blogspot.com/

The 6 Things You Need To Do If You Are Exposed To Mercury

Nov 26, 2012

"Odds ratios (ORs) were increased for the usual risk factors for breast cancer and, adjusting for these, risks increased with occupational exposure to several agents, and were highest for exposures occurring before age 36 .

http://workers-compensation.blogspot.com/

Occupational Exposure to Silica During Hydraulic Fracking

May 24, 2012

While focus has been on environmental concerns with the advent of fracking, a process to release oil and gas, a new concern has emerged over the potential occupational exposure to silica by workers who are involved in the ...

http://workers-compensation.blogspot.com/

Breast Cancer Linked to Occupational Exposures - Workers ...

May 29, 2010

"Odds ratios (ORs) were increased for the usual risk factors for breast cancer and, adjusting for these, risks increased with occupational exposure to several agents, and were highest for exposures occurring before age 36 ...

http://workers-compensation.blogspot.com/

Related articles

• Why Injured Workers Should Deactivate Their Social Media Accounts (workers-compensation.blogspot.com)
• The Hidden Cost of Jobs - Selling Fear (workers-compensation.blogspot.com)
• Hot Topics in Workers Compensation Law 2013 (workers-compensation.blogspot.com)
• US Supreme Court Hears Oral Argument on Workplace Harassment Case (workers-compensation.blogspot.com)
• The Devil is in the Details California Style (workers-compensation.blogspot.com)

Virus on Board: Are We Ready?

Hantavirus, the Andes Strain, and the Workers' Compensation System's Preparedness for Person-to-Person Infectious Disease Outbreaks

The Compensability of a Cellphone Radiation Exposure

A pending case in California may have significant impact on potential workers’ compensation claims throughout the country. The case involves the causal relationship of radio frequency [RF] radiation emitted by cellphones and human cancer. Cohen v. Apple, Inc., et. al, Case 5:19-cv-05322 (Filed 08/23/19) USDCT-North District California - San Jose Division.

Workers’ Compensation Benefits for Occupational Exposure to Cellphone Radiation

Last week, the French government requested that Apple stop selling the iPhone 12 model because of excessive radiation detected during recent tests. The Agence National des Fréquences [ANFR] stated that “…Apple must immediately take all measures to prevent the availability on the market of the phones concerned present in the supply chain. Regarding phones already sold, Apple must take corrective measures as soon as possible to make the phones concerned compliant. Otherwise, it will be up to Apple to recall them.”

Workplace Toxins: A Hidden Epidemic

In his groundbreaking new book, The Formula for Better Health: How to Save Millions of Lives—Including Your Own, former CDC Director Dr. Tom Frieden draws on decades of experience leading public health efforts to reveal how to defeat the world's deadliest diseases. While the book covers many health threats, its principles are particularly relevant to one of America's most overlooked crises: occupational exposure to toxic substances.

Protecting Healthcare Heroes: Pandemic Preparedness

The 2025 Global Preparedness Monitoring Board (GPMB) report, The New Face of Pandemic Preparedness, arrives with a sobering message: five years after COVID-19 began, the world remains dangerously unprepared for the next pandemic. But perhaps nowhere is this vulnerability more acute than among healthcare workers and first responders—the very people we depend on when crisis strikes.

Beryllium Exposure Standard Enforcement Delayed Until May 2018

The Trump Administration has yet again delayed the implementation of a stricter standard for occupational exposure to beryllium. The new date for enforcement is May 11, 2018.

Trump Administration May Bring a Surge in Occupational Disease Claims

Mesothelioma death rates remain high in the US even on the eve of an anticipated national ban of the asbestos fiber. Things may radically change for the worse as the Trump Administration goes forward with its announced intention to dismantle environmental regulation now in place and placed on-track for enactment during the former Obama Administration. With anticipated less EPA and OSHA regulation under the Trump administration, there is the potential for a serious surge of future occupational disease claims in the United States.

Toxic Lead Exposure Results in OSHA Fines for NJ Company

Exposure to lead can cause serious medical problem in both children and adults. Strict safety precautions must be observed when working with lead.

Many initial occupational exposure claims in workers' compensation resulted from the

exposure to lead in factories. Lead pigment was used in paints for many years leading to a many serious blood disorders and neurological conditions.

The U.S. Department of Labor's Occupational Safety and Health Administration has cited Henry RAC Holding Corp. with four repeat and four serious safety and health violations, including workers exposed to lead hazards, at the company's Bayonne facility. The inspection was initiated in September 2012 after health hazards were discovered during an earlier OSHA safety inspection at the facility. Proposed penalties total $72,000.

EPA's Asbestos Rule Awaits Data

How EPA's Request for Information on Legacy Asbestos Fits Into the Regulatory and Workers' Compensation Picture

Gatekeeping Scientific Evidence Post-2023

Analyzing Special Master Wolfson's Comprehensive Framework for Expert Testimony Admissibility

Analysis of US EPA's Draft Risk Evaluation for Formaldehyde and Worker Health

The U.S. Environmental Protection Agency's (EPA) draft risk evaluation of formaldehyde, released on March 15, 2024, raises significant concerns for worker health and worker compensation risk exposure.

EC Publishes Criteria to Diagnose Occupational Illness

The European Commission has published a listing of the criteria for diagnosis occupational disease. The 272 page report is available on-line. It reviews hundreds of established occupational medical conditions.

a) The clinical features must fit in with what is known about the health effects following  exposure to the specified agent. The symptoms and signs should fit, and this may be supported in some cases by suitable diagnostic tests.

b) There must be indication of sufficient occupational exposure. Evidence on exposure may be obtained through taking the occupational history, results of occupational hygiene measurements taken at the workplace, biological monitoring results, and/or records of incidents of over-exposure.

c) The time interval between exposure and effect must be consistent with what is known about the natural history and progress of the disease. Exposure must precede health effects. However, in some conditions such as occupational asthma, a past history of childhood asthma and/or asthmatic attacks occurring before occupational exposure, does notautomatically rule out the possibility of a workplace agent causing subsequent asthmatic attacks.

d) The differential diagnosis must be considered. There are non-occupational conditions that have similar clinical features as occupational diseases, and a physician will have to take this into account before diagnosing or excluding an occupational disease.


To read more about occupational exposures and workers' compensation.

Click here for more information on how Jon L Gelman can assist you in a claim for workers' Compensation claim benefits. You may e-mail Jon  Gelman or call 1-973-696-7900.