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(c) 2010-2024 Jon L Gelman, All Rights Reserved.

Tuesday, October 28, 2014

IMIG 2014: Mesothelioma: Cancer stem cells by defactinib, a novel inhibitor of FAK


Paul Baas summarizes evidence from studies showing specific targeting of cancer stem cells by defactinib, a novel inhibitor of FAK.

IMIG 2014: Dr. Ravi Salgia presents “From Chaos to Mitochondrial Functionality”

Dr. Salgia summarized efforts from his group to bring mathematical modeling to the study of malignant mesothelioma and how the rules of this theory can be applied to consideration of mutations associated with mesothelioma, suggesting that DNA acts much likes fractals. He emphasized that the fractal dimensionality of mesothelioma cells is dramatically different from that of normal cells and that mitochondrial networks in mesothelioma can also be modeled with fractal analysis. Click here to learn more about this new approach to understanding mesothelioma and the biology of other cancer cells.

Click here to watch Dr. Salgia’s Presentation

Ebola Policies Made in Panic Cause More Damage

With good reason, Americans are deeply confused about the risks of Ebola. It is a frightening disease, made more so by dueling theories about how best to deal with people arriving from West Africa and by wildly different messages — based partly on erroneous information given out by New York City officials — about whether the doctor who returned to New York from treating patients in Guinea and came down with the disease was or was not a danger to others when he moved around the city.
To make matters worse, two ambitious governors — Chris Christie of New Jersey and Andrew Cuomo of New York — fed panic by imposing a new policy of mandatory quarantines for all health care workers returning from the Ebola-stricken countries of West Africa through John F. Kennedy and Newark Liberty international airports. There is absolutely no public health justification for mandatory quarantines.
It’s not surprising that they have started to adjust their earlier positions, which seemed politically motivated, as they have come under a barrage of criticism from public health experts for their dangerous overreaction. They now say they will allow health care workers to be confined to their own homes, where they will be checked twice a day by public health officials.
Lost in this grandstanding was one essential point. The danger to the public in New York in the case of Dr. Craig Spencer, who had worked in Guinea for Doctors Without Borders, was close to nonexistent....
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California is most expensive state for workers' comp

Ouch -- the cost of workers' compensation in California is more expensive than any other state in the nation, a new study says.

The Workers' Compensation Premium Rate Ranking Summary from Oregon's Department of
Today's post is shared from
Consumer and Business Services reveals that California businesses spend $3.48 for every $100 of payroll issue on workers' comp expenses.

The ranking demonstrates a trend, as California was the third-most expensive state in 2012 and the fifth-most expensive in 2010, the Los Angeles Daily News reports.

The $3.48 mark represent a 188 percent of the median cost of $1.85 for all 50 states.

Separately, a new study looking at the 2013 fee schedule changes projects that California workers comp office visit payments will increase 8 percent overall.

"California's workers' compensation system is incredibly inefficient," said Jerry Azevedo, a spokesman for the California-based Workers' Compensation Action Network, told the Daily News.

Azevedo's group aims to reduce costs for employers and improve services to injured workers.

Second on the list is Connecticut, at $2.87 of every $100 in payroll going toward workers' compensation costs. The top five are rounded out by New Jersey ($2.82), New York ($2.75) and Alaska ($2.68).

Ranking lowest was North Dakota, where a mere 88 cents of every $100 in payroll goes toward workers' comp costs.

Scott Bridges has covered the Los Angeles scene for over ten years as a journalist and food critic. Follow him on the...
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Hospitals’ Struggles To Beat Back Familiar Infections Began Before Ebola Arrived

Today's post was shared by Kaiser Health News and comes from kaiserhealthnews.org

While Ebola stokes public anxiety, more than one in six hospitals — including some top medical centers — are having trouble stamping out less exotic but sometimes deadly infections, federal records show.

Nationally, about one in every 25 hospitalized patients gets an infection, and 75,000 people die each year from them—more than from car crashes and gun shots combined. A Kaiser Health News analysis found 695 hospitals with higher than expected rates for at least one of the six types of infections tracked by the federal Centers for Disease Control and Prevention. In 13 states and the District of Columbia, a quarter or more of hospitals that the government evaluated were rated worse than national benchmarks the CDC set in at least one infection category, the KHN analysis found.

The missteps Texas Health Presbyterian Hospital made this month in handling an Ebola patient echo mistakes hospitals across the nation have made in dealing with homegrown infections. Dr. Kevin Kavanagh, a patient safety expert from Kentucky, said hospitals too often don’t strictly follow protocols to deal with infectious diseases, and the government’s standard responses are not specific enough. “Right now there are too many recommendations on how to handle infectious diseases, too much leeway,” he said.

A 2011 study in the New England Journal of Medicine underscored the problem, observing that while hospitals have reduced the frequency...
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Nurses to Jerry Brown: California isn’t ready for Ebola

Today's post was shared by CAAA and comes from www.sacbee.com

The state’s largest nurses union said Tuesday that no California hospital is prepared to treat an Ebola patient, pressing Gov. Jerry Brown to require increased training and protective equipment for nurses.
The union’s call – and a rebuttal from the California Hospital Association – came as Brown met privately with nurses, public health officials and medical providers to discuss Ebola.
Though there are no known cases of Ebola in California, the virus has gripped public attention since an outbreak in West Africa and the infection of two nurses treating an Ebola patient who died in Texas earlier this month.
The Brown administration issued no mandates but said in a prepared statement that “officials are taking steps to help ensure health care workers, hospitals and first responders are prepared to treat and care for patients with Ebola.”
RoseAnn DeMoro, executive director of the California Nurses Association and National Nurses United, said California hospitals have failed to provide adequate training or equipment to nurses, a claim hospitals disputed.
“None of the hospitals in California are prepared,” DeMoro said after meeting with Brown. “We cannot name a hospital that we feel comfortable with, for patients in the state of California to attempt to have the appropriate response in an Ebola situation.”
Speaking at a news conference outside Brown’s offices at the Capitol, DeMoro said, “The deficiencies in the...
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Cuomo and Christie's Ebola Tag-Team

Today's post was shared by Steven Greenhouse and comes from www.bloomberg.com

Andrew Cuomo took the low road.
On Thursday night, the night Ebola officially, dauntingly, came to Gothamtown, the governor sat to Mayor Bill de Blasio's left at a news conference and tried to calm New Yorkers’ nerves. The two Democrats appeared at Bellevue Hospital, the country’s oldest continually operating hospital, an international leader in treating infectious diseases and one of eight facilities the state had designated for Ebola treatment. The presence of the governor and mayor, mere floors beneath the room where the infected patient, Dr. Craig Spencer, remained in quarantine, highlighted that the virus does not travel by air. Like President Obama’s hug with Nina Pham—the 26-year-old Dallas nurse who contracted Ebola from Thomas Eric Duncan, and blessedly had overcomethe virus after a period of isolation—their news conference was a gesture meant to reassure the city's anxious citizenry: Ebola is transmitted only through the sharing of bodily fluids. Rest assured, 8.4 million residents of New York City, 19.6 million citizens of New York State. Do not be alarmed.
De Blasio told New Yorkers that the chances of becoming infected by Ebola were vanishingly small. “We have the finest public health system not only anywhere in the country but anywhere in the world,” he said. Cuomo added, “We are as ready as one could be for this circumstance.” On...
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